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A multi-disciplinary team of world-leading doctors & health experts

Doctors

Penelope Tympanidis, PhD, MS | Founder of Life Line Genomics

Dr Penelope Tympanidis is a UK trained Consultant Dermatologist.After graduating with honors (110 cum laude) from the University of Rome School of Medicine, she trained under scholarship at Tufts Medical school, New England Medical Centre, on cutaneous surgery. Dr Tympanidis subsequently embarked on a training rotation in the UK. This involved a 2 year research MD, at the Royal Free Medical Campus, and 4years of intense clinical work.

Dr Tympanidis has worked as Consultant Dermatologist for Coydon hospital, Imperial healthcare, and CDS (Central London Community Dermatology service), where assumed the role of clinical governance lead, teaching GPs.

Dr Tympanidis runs a Harley street private practice since 2002, offering general and Cosmetic Dermatology treatments. She has been a pioneer on therapeutic chemical peels,acne scars treatment, facial sculpting, and minimally invasive anti-ageing procedures. She regularly trains junior doctors on all the above procedures.Her most recent venture is the result of a decade research on ageing markers, which lead to epigenetic testing of her patients to prevent skin ageing, and disease that leads to senility. This groundbreaking novelty, is backed by scientists from NIH Washington DC, and a group of highly competent specialists in different medical fields, offering a 360 degree of healthcare, and age/disease prevention.

– Regular lecturer at UCL/Middlesex Hospitals on common skin diseases.

– Conducted clinical teaching days for medical students and junior doctors.

– Led GP teaching sessions to reduce dermatology referrals and update therapeutic trends.

– Organized and led workshops on minimally invasive cosmetic procedures and anti-aging techniques for plastic surgeons and dermatologists.

Participated as an investigator in multiple clinical trials, including:

  •  Topical Calcipotriol for facial psoriasis (LEO Pharmaceuticals)
  • Fucibet cream for overinfected eczema (LEO Pharmaceuticals)
  • SDZ ASM 981 cream for atopic eczema (Novartis)
  • Marimostat tablets for psoriasis
  • Tazarotene gel with UVB phototherapy for psoriasis (Allergan)

 

  • MD Thesis: “Increased innervation of the vulval vestibulus in patients with vulvodynia.”

Multiple peer-reviewed publications in leading dermatology journals, including:

  • Tympanidis P., N.Kapur, R.Yu. (January 2002): “Hepatitis C virus associated, type II, mixed cryoglobulinaemia. A case report, and retrospective of 20 years’ follow-up” (Clinical and Experimental Dermatology).
  • Tympanidis P., Lakhani S., Groves R.W.: “Progesterone-receptor positive clear cell syringoma associated with diabetes.” (Journal of the American Academy of Dermatology).
  • Tympanidis P., Terenghi G., Dowd P.M.: “Increased innervation of the vulval vestibule in patients with vulvodynia” (British Journal of Dermatology, 2003).
  • Penelope Tympanidis, Maria Anna Casula, Yiangos Yiangou, Giorgio Terenghi, Pauline Dowd, Praveen Anand: “Increased vanilloid receptor VR1 innervation in vulvodynia” (European Journal of Pain, April 2004).
  • C. C. Zouboulis, P. Tympanidis, T. Tzellos, et al.: “Hidradenitis suppurativa severity score system (HS4): preliminary results” (Experimental Dermatology, 2016).


Specialist Training & Conferences:

  • Completed advanced training courses in dermatological surgery and skin biology.
  • Attended and presented at prestigious dermatology conferences worldwide, including:
    • American Academy of Dermatology (AAD) Annual Meetings
    • European Society for Pediatric Dermatology Congress
    • Society for Investigative Dermatology (SID) Meetings
    • World Congress of Dermatology
    • Dubai Derma and FACE Conference (London)


Presentations & International Recognition:

  • Presented over 20 research papers and clinical findings at international dermatology conferences.
  • Notable presentations include:
    • “Transplacental Transfer of Anti-Tyrosinase IgG Antibody Resulting in Vitiligo in a Newborn” (San Francisco, 2000)
    • “Clinical Applications of 3D Fringe Topography Technique in Dermatology” (Boston, 1998)
    • “Hidradenitis Suppurativa: Alternative Treatment Options” (Brussels, 2015)
    • “Botulinum Toxin and Dermal Fillers: Pitfalls to Avoid” (Royal Society of Medicine, 2015)


Contributions to Dermatology:

  • Developed innovative diagnostic methods for skin disorders using 3D microtopography.
  • Conducted pioneering research in vulval dermatology and dermatological neurophysiology.
  • Contributed to the European Hidradenitis Suppurativa Foundation’s severity score system.
  • Designed clinical studies on natural treatment alternatives for vulval dermatological conditions.
    •  

Future Research Interests:

  • Skin Surface Profilometry:
    • Developing accurate methods for assessing and tracking skin lesions and wound healing.
    • Collaborating with optical engineers to create low-cost, reproducible dermatological diagnostic techniques.
    • Exploring applications in plastic surgery for lesion measurement at micron-level precision.
  • Neurophysiology of Vulvodynia:
    • Investigating neuropeptides and neurotrophins involved in vulvodynia pathogenesis.
    • Running a dedicated vulval clinic for conditions such as prurigo vulvae, lichen sclerosus, and vulvodynia.
    • Leading a clinical study with gynecology consultants on natural, licensed compounds for vulval disease treatment.

Sotiris N Nikolopoulos, PhD, MS

Dr. Sotiris N. Nikolopoulos is a distinguished scientist and entrepreneur with a robust background in molecular and cellular biology. As the Founder and Scientific Director of the Center for Molecular Analysis and Research SA in Greece, he has been a driving force in advancing scientific research and discovery. He holds a Bachelor of Science in Biology from the National and Kapodistrian University of Athens, a Master of Science in Medical Biology (Immunology) from Long Island University, Brookville, NY, and a Ph.D. in Molecular and Cellular Biology at Fordham University.

Dr. Nikolopoulos holds a series of prestigious fellowships that shaped his expertise. He has served as a Fellow in Molecular and Cellular Biology at SUNY Upstate Medical University, Syracuse, NY and in Molecular and Cellular Oncology at the renowned Memorial Sloan-Kettering Cancer Center in New York.

Throughout his career, Dr. Nikolopoulos has been recognized for his outstanding contributions and received numerous honors and awards. Notably, he was awarded the National Institutes of Health (NIH) Fellowship, Ruth L. Kirschstein National Research Service Award, during his time at Memorial Sloan-Kettering Cancer Center from July 2003 to July 2006. His dedication was also acknowledged with the American Heart Association Fellowship at SUNY Upstate Medical University from July 1999 to June 2002. Dr. Nikolopoulos has actively published research articles in reputable scientific journals. His selected publications, such as those in Oncogene, Journal of Cell Biology, and Cancer Cell, showcase the depth and significance of his contributions to the field.

POSITIONS

  • Apr 2007-current: President and Scientific Director, Center for Molecular Analysis and Research SA, Greece
  • Sep 2001-July 2006: Fellow in Molecular and Cellular Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • Sep 1998-Sep 2001: Fellow in Molecular and Cellular Biology, SUNY Upstate Medical University, Syracuse, NY
  • Sep 1990- Dec 1996 PhD in Molecular and Cellular Biology, Fordham University, Bronx, NY
  • May 1989- Sep 1990: Technologist II, North Shore University Hospital, Manhasset, NY
  • Sep 1987- May 1989 MS in Medical Biology (Immunology), Long Island University, Brookville, NY
  • Sep 1982- May 1987 BS in Biology, National and Kapodistrian University of Athens, Athens, Greece

HONORS / AWARDS

  • National Institutes of Health (NIH) Fellowship, Ruth L. Kirschstein National Research Service Award (July 2003-July 2006), Memorial Sloan-Kettering Cancer Center, New York, NY
  • American Heart Association Fellowship, NY State Affiliate (July 1999 – June 2002), SUNY Upstate Medical University, Syracuse, NY
  • Postdoctoral fellowship, intramural SUNY (October 1998 – October 1999), SUNY Upstate Medical University, Syracuse, NY
  • Presidential Fellowship, Fordham University, Bronx, NY (Sep 1993-Dec 1996), Bronx, NY
  • Certificate of Merit for outstanding performance, dedication and effort in achieving the goals of North Shore University Hospital (April 1990), Manhasset, NY
  • Dean’s award for academic excellence in graduate studies, School of Health Professions, Long Island University (May 1989), Brookville, NY

SELECTED PUBLICATIONS

  • Nikolopoulos SN, Spengler BA, Kisselbach K, Evans AE, Biedler JL, Ross RA (2000). Oncogene 19:380-386.
  • Nikolopoulos SN and Turner CE (2000). Journal of Cell Biology 145:851-863.
  • Nikolopoulos SN and Turner CE (2001). Journal of Biological Chemistry 276:23499-23505.
  • Nikolopoulos SN and Turner CE (2002). Journal of Biological Chemistry 277:1568-1575.
  • Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG (2004). Cancer Cell 6:471-483.
  • Nikolopoulos SN and Giancotti FG (2005). Cell Cycle 4(3):429-433.
  • Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Puri C, Tacchetti C, Giancotti FG (2005). Molecular and Cellular Biology 14: 6090-6102.

Penelope Tympanidis, PhD, MD

Founder

Dr Penelope Tympanidis is a UK trained Consultant Dermatologist. After graduating with honors (110 cum laude) from the University of Rome School of Medicine, she trained under scholarship at Tufts Medical school, New England Medical Centre, on cutaneous surgery. Dr Tympanidis subsequently embarked on a training rotation in the UK. This involved a 2 year research MD, at the Royal Free Medical Campus, and 4 years of intense clinical work.

Dr Tympanidis has worked as Consultant Dermatologist for Coydon hospital, Imperial healthcare, and CDS (Central London Community Dermatology service), where assumed the role of clinical governance lead, teaching GPs.

Dr Tympanidis runs a Harley street private practice since 2002, offering general and Cosmetic Dermatology treatments. She has been a pioneer on therapeutic chemical peels,acne scars treatment, facial sculpting, and minimally invasive anti-ageing procedures. She regularly trains junior doctors on all the above procedures. Her most recent venture is the result of a decade research on ageing markers, which lead to epigenetic testing of her patients to prevent skin ageing, and disease that leads to senility. This groundbreaking novelty, is backed by scientists from NIH Washington DC, and a group of highly competent specialists in different medical fields, offering a 360 degree of healthcare, and age/disease prevention.

Sotiris N Nikolopoulos, PhD, MS

Dr. Sotiris N. Nikolopoulos is a distinguished doctor and scientist with a robust background in molecular and cellular biology. As the Founder and Scientific Director of the Center for Molecular Analysis and Research SA in Greece, he has been a driving force in advancing scientific research and discovery. He holds a Bachelor of Science in Biology from the National and Kapodistrian University of Athens, a Master of Science in Medical Biology (Immunology) from Long Island University, Brookville, NY, and a Ph.D. in Molecular and Cellular Biology from Fordham University.

Dr. Nikolopoulos holds a series of prestigious fellowships that shaped his expertise. He has served as a Fellow in Molecular and Cellular Biology at SUNY Upstate Medical University, Syracuse, NY and in Molecular and Cellular Oncology at the renowned Memorial Sloan-Kettering Cancer Center in New York.

Throughout his career, Dr. Nikolopoulos has been recognized for his outstanding contributions and received numerous honors and awards. Notably, he was awarded the National Institutes of Health (NIH) Fellowship, Ruth L. Kirschstein National Research Service Award, during his time at Memorial Sloan-Kettering Cancer Center from July 2003 to July 2006. His dedication was also acknowledged with the American Heart Association Fellowship at SUNY Upstate Medical University from July 1999 to June 2002. Dr. Nikolopoulos has actively published research articles in reputable scientific journals such as Oncogene, Journal of Cell Biology, and Cancer Cell.

Clinic Management & Patient Coordination

Euthymia Anthi

With a keen focus on precision and efficiency, and more than 20 years of experience, Euthymia plays a crucial part in the holistic success of our programs. Her responsibilities encompass overseeing every aspect of your journey, ensuring that each phase operates harmoniously and aligns with your overarching goals. By meticulously coordinating and optimizing each patient’s pathway, Euthymia contributes significantly to the overall success and effectiveness of our operations, fostering a streamlined and patient-centric approach.